Abstract:

The Dsup protein is a new protein discovered in 2016 in the tardigrade Ramazzottius varieornatus, one of the most radioresistant species of multicellular organisms. The generation of D. melanogaster lines and human cell culture expressing this protein allows evaluating the possibility of increasing their radioresistance after exposure to various types of ionizing radiation, and a wide range of methods applicable to these model organisms makes it possible to study Dsup molecular mechanisms. In connection with the project prolongation.